Reinforced concrete beam with a recess contains discontinuity regions (D-regions) owing to the abrupt change in the beam' depth. Thus, stress concentration is developed around the recess, which may result in premature failure due to improper detailing for such region. This paper presents the results of an experimental program performed on reinforced self-compacting concrete beams with two recesses in both compression and tension side of the beams. Ten beams were configured and casted then tested up to failure under the effect of repeated loading. The test variables included the location of the recess, size of the recess, and the reinforcement detailing around the recess in the tension zone. Test results revealed that the ultimate capacity of beams with recesses reduced by about 25 to 60% compared to that of similar solid beam. It was found that non-prismatic beams with a recess in compression zone performed better than beams having a recess in tension zone from the viewpoint of deflection and the cracking pattern. Finally the configuration of the reinforcement detailing around the recess in the tension zone showed changes in the initial stiffness, ductility and modes of failure and thus the most efficient steel configuration was identified.