Simsima limestone is a kind of rock with karst features and anisotropic characteristics commonly found in Qatar peninsula. This layer normally extends down to about 30 m depth from the ground surface forming the foundation layer for most of the engineering projects. It is generally characterized by anisotropic condition due to the presence of numerous vugs and irregular joints often filled with weak materials. Because of this complex formation and the difficulty in retrieving intact samples of proper sizes for lab testing using the uniaxial compression strength tests (UCS), the importance of performing point load strength tests arises as a simple and quick tool to characterize the rock formation from the strength perspective necessary for civil engineering projects. Several correlations are presented in the literature correlating the UCS to the point load strength index (Is50), where the resulting equations vary greatly with the variation of the rock type, strength and geological conditions. In this paper, 167 UCS and corresponding Is50 results of the Simsima limestone formation were collected from eight different locations across the state of Qatar and were studied aiming at finding the best correlation between them. Different regression models varying between linear, quadratic and cubic were investigated showing that, the polynomial regression models are the favorable approaches but just over certain ranges of the Is50 values (i.e. Is50 ≤ 5.0 MPa for the quadratic model and Is50 ≤ 3.0 MPa for the cubic model). Emphasis was given to the linear regression model as the most commonly used type worldwide. The performed analyses showed that the constant factor correlating the UCS and the Is50 values varies depending on the rock strength classification between approximately 4.0, 7.4 and 13.6 for the weak, medium strong and strong Simsima limestone respectively. An average constant value of approximately 7.6 for mixed strengths rocks might be used. The point load strength tests are not recommended to be used solely for characterizing the Simsima limestone while their values might be used for preliminary assessment.