A field experiment was conducted during winter 2020/21 and 2021/22 seasons at the Agronomy Department Farm, Agriculture Faculty, Assiut University, to examine the effect of foliar spray with some growth stimulators on the yield and its attributes of four bread wheat cultivars. The experiment was laid out in randomized complete block design (RCBD) using strip plot arrangement with three replications. Foliar sprays containing distilled water (solvent as a control), Moringa Extract, Humic Acid, Chitosan, and Seaweed Extract (Acadian) at concentrations of 13,000, 4,000, 500 and 2500 ppm, respectively were dispersed horizontally and the bread wheat cultivars Gemmiza-11, Giza-171, Shandaweel-1, and Sids-14 were arranged vertically. Plant height, spike length, grain number spike^-1, 1000 grains weight, grains spike weight, and grain yield were significantly affected by foliar spraying treatments with growth stimulators in both seasons. The highest average values of the aforementioned traits were found in wheat plants sprayed with Moringa Extract. Additionally, the traits examined were significantly influenced by the cultivars under study. Gemmiza-11 cultivar produced the greatest values of all examined traits in both seasons. The interaction between some growth stimulators and cultivars affected significantly grain yield fed^-1 in both seasons. Gemmiza-11 cultivar sprayed with Moringa Extract in both seasons produced the highest grain yield values in both seasons (26.12 and 26.18 ardab fed.^-1, respectively) for the, which was.