The main aim of the current study was to improve the production of oil from sesame seeds by optimizing the extracting screw speed and extracting temperature. To achieve that, the effect of different extraction temperatures (45, 55, and 65 °C) and different extraction screw speeds (75, 90 and 120 rpm) on the oil extraction yield, extraction efficiency, extraction energy requirements and extraction time were investigated. The results most important indicate that the sesame oil yield increased from 49.6 to 52.4, 49.2 to 52.0 and 48.0 to 51.2 %, when the extracting temperature increased from 45 to 65 ºC, for 75, 90, and 120 rpm screw speeds, Respectively.  The highest value of the extraction efficiency (84.52%) was obtained at 65 °C extracting temperature and 75 rpm screw speed. The lowest value of the extraction time (2.203 min) was observed at 65 ℃ extracting temperature and 120 rpm screw speed. The optimal specific energy consumption of 0.215 kW.h/kg_oil was obtained at 65 °C extracting temperature and 120 rpm screw speed.