Background: The exploration of aloe vera's effects on pressure ulcer (PU) healing offers a promising avenue for enhancing wound care, particularly in bed ridden patients. As research continues, it holds the potential to improve healing rates and overall patient quality of life. Aim of the study: evaluate the effect of Aloe vera on pressure ulcer healing among bed-ridden patients. Research design: A quasi-experimental research design (study/control) was utilized in the current study. Setting: The current research was conducted in the Gastrointestinal and hepatic hospital (Medical Intensive Care Unit & Main Minia University Hospital (Medical Care Unit & Trauma Intensive care unit), Minia city, Egypt. Sample: A purposive sample of 60 patients was randomly assigned to study and control group (30 for each). Tools: Tool I: Personal and medical assessment sheet, Tool II: BATES- JENSEN wound assessment tool, consisted of thirteen assessment parameters that was used to investigate wound status. Results: The study findings showed that time of healing, it was found that PU healed faster among study group (20%) after 1^st week. In contrast (3.3%) of the control group had a PU that not healed within the 1^st week of observations, with highly statistical significant differences between the study and control groups regarding exact time of complete PU healing according BATES JENSEN Wound Assessment. Conclusion: Aloe vera had positive effect on the recovery process of pressure ulcer among bedridden patients with low cost and easy techniques. Recommendation: Use of Aloe vera is effective for healing of pressure ulcers.