The community usage of insecticide sprays and associated factors among residents of Delta 
State, Nigeria, was measured. This cross-sectional study assessed 450 respondents, selected 
from 3 local government areas (LGAs) of Delta State through multi-stage cluster sampling. A 
pretested, structured, and open-ended questionnaire was adopted. The socio-demographics 
and economics of respondents, their knowledge, attitude, and insecticidal usage practice were 
assessed, as well as the insecticides type available in the area. About 48% of the pooled 
studied participants used different insecticide brands based on how effective (58%), safe 
(≈44%), comfortable (≈33%), affordable (≈26%), and available insecticides were (p>0.05).  
Household preferred the insecticide brands was significantly dependent on the dwelling/ ho
use types and locations (p<0.05). Most respondents used Raid insecticides every 1-2 days per 
week (18%). The education level, dwelling type, and financial status of participants were 
significant determinants of insecticidal application time (p<0.05). The insecticidal spraying 
level was below WHO's target of 80% coverage. Respondent's knowledge was moderate, but 
their attitude and practice were low. Adequate health care education on knowledge, attitude, 
and practice, as well as finance, should be considered in designing routine guidelines for the 
indoor residual spray (IRS). This could effectively help in managing insecticidal resistance.