Background: Recent studies suggest that partial pulpotomy results in less postoperative pain than conventional root canal treatment.
Methods: A randomized controlled trial was conducted among young patients with age ranged between nine to fourteen years old to compare postoperative pain intensity after treatment of young permanent molars diagnosed with symptomatic irreversible pulpitis that was treated by either partial pulpotomy using putty MTA or traditional endodontic therapy. Statistical analysis was done by Chi-square test to compare between tested groups. The significance level was set at P ≤ 0.05. Results: Compared to the root canal treatment group, the partial pulpotomy group showed lower mean pain score levels at 24, 48, and 72 hours with a statistically significant difference at 48 hours only. Conclusions: Partial pulpotomy using bioceramics proved to have reduced postoperative pain than cases treated with full RCT when managing young permanent teeth with symptomatic irreversible pulpitis. Trial registration: The trial was registered with ClinicalTrials.gov on July 7, 2023, and given the identification number NCT05956613.