ManageChatDiscover
425414

Serological Detection of Anti-Toxoplasma gondii Antibodies Using Lateral Flow Device

Article

Last updated: 04 May 2025

OverviewSimilar Items

Subjects

-

Tags

Diagnostics

Abstract

Background: Toxoplasmosis, caused by the intracellular protozoan Toxoplasma gondii, is a parasitic disease affecting warm-blooded animals, including humans. It poses severe risks to newborns and immunocompromised individuals. Detecting specific IgG and IgM antibodies used for diagnosis of suspected toxoplasmosis. Subjective: This study aimed to assess T. gondii infection prevalence among female students at the University of Basrah, focusing on those with direct cat contact. Methodology: Using Lateral Flow Immunoassay, IgG and IgM antibodies were detected to identify infections. A cross-sectional study was conducted from April to June 2024, involving 100 female participants with cat exposure, with a mean age of 22 years old. Data on age, cat type, glove use, and symptoms were collected via a questionnaire. Results: The results revealed 9 (18%) positive cases (IgM-/IgG+) and 41 (82%) negative cases among exposed individuals. Over 80% did not wear masks and gloves during cat litter cleaning. Common clinical symptoms included headache with vision disorders (34%), and headache with fatigue (30%). The remaining 25% were asymptomatic. All infected individuals had cat contact or exposure to infection sources, with stray cats being the most common associated type. Conclusions: All patients had a history of contact with cats or other potential sources of T. gondii infection, with stray cats identified as the most common type associated with these infections.

DOI

10.21608/ejmm.2025.374464.1561

Keywords

Toxoplasma, gondii, antigen, LFD, Immunocompromised

Authors

First Name

Marwan

Last Name

Al-Maqtoofi

MiddleName

Y.

Affiliation

Department of Biology, College of Science, University of Basrah, Basrah, 61004, IRAQ

Email

marwan.almaqtoofi@uobasrah.edu.iq

City

Basrah

Orcid

0000-0001-6126-7874

First Name

Ahmed

Last Name

Hussein

MiddleName

J.

Affiliation

Department of Biology, College of Science, University of Basrah, Basrah, 61004, IRAQ

Email

immunotech22zx@gmail.com

City

Basrah

Orcid

-

First Name

Shahed

Last Name

Jabir

MiddleName

A.

Affiliation

Department of Biology, College of Science, University of Basrah, Basrah, 61004, IRAQ

Email

kanimani2030@gmail.com

City

Basrah

Orcid

-

Volume

34

Article Issue

4

Related Issue

54773

Issue Date

2025-10-01

Receive Date

2025-04-10

Publish Date

2025-10-01

Print ISSN

1110-2179

Online ISSN

2537-0979

Link

https://ejmm.journals.ekb.eg/article_425414.html

Detail API

http://journals.ekb.eg?_action=service&article_code=425414

Order

425,414

Type

New and original researches in the field of Microbiology.

Type Code

2,038

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

Serological Detection of Anti-Toxoplasma gondii Antibodies Using Lateral Flow Device

Details

Type

Article

Created At

04 May 2025