ManageChatDiscover
425475

Inflammatory Biomarkers as Prognostic and Predictive Factor in Patients with COVID-19

Article

Last updated: 04 May 2025

OverviewSimilar Items

Subjects

-

Tags

Diagnostics

Abstract

Background: COVID-19 severity is often linked to excessive inflammatory responses. Biomarkers such as C-reactive protein (CRP), IL-17, and IL-33 have potential roles in inflammation and disease progression. Identifying these biomarkers may help predict disease severity and guide clinical management. Objective:  This study aimed to investigate the role of CRP, IL-17, and IL-33 as indicator factors for Covid-19 severity. Methodology: The study involved ninety-five Covid-19 patients divided into mild and severe, along with (50) healthy controls.  Levels of CRP, IL-17 and IL-33 were measured by ELISA in patients and healthy controls. Results: The results of the study indicated highly significant relation between the Covid-19 groups and healthy controls regarding C-reactive protein levels, as well as Il-17 and IL-33. Conclusion: The biomarkers are highly associated with Covid-19. Increased levels of IL-17, IL-33 facilitates lung injury through production other pro-inflammatory cytokines and that explain the immunopathology of Covid-19 infection, so could be used as a predictive factor for intensity of disease in patients with COV1ID-19.

DOI

10.21608/ejmm.2025.373367.1551

Keywords

lung injury, Cytokine Storm, IL-33 level

Authors

First Name

Wafaa

Last Name

Hamad

MiddleName

F.

Affiliation

College of Health and Medical Techniques, Baghdad, Middle Technical University, Baghdad, Iraq

Email

wfhh1977@mtu.edu.iq

City

-

Orcid

-

First Name

Radhia

Last Name

Fadel

MiddleName

H.

Affiliation

Department of Medical Laboratory Techniques, College of Health and Medical Techniques/ Kufa, Al-Furat Al-Awsat Technical University, 31003 Al-Kufa, Iraq

Email

kuh.radhia@atu.edu.iq

City

-

Orcid

-

Volume

34

Article Issue

3

Related Issue

53640

Issue Date

2025-07-01

Receive Date

2025-04-07

Publish Date

2025-07-01

Print ISSN

1110-2179

Online ISSN

2537-0979

Link

https://ejmm.journals.ekb.eg/article_425475.html

Detail API

http://journals.ekb.eg?_action=service&article_code=425475

Order

425,475

Type

New and original researches in the field of Microbiology.

Type Code

2,038

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

Inflammatory Biomarkers as Prognostic and Predictive Factor in Patients with COVID-19

Details

Type

Article

Created At

04 May 2025