Background and Aim: The reflux symptoms score -12 (RSS-12) is a validated questionnaire with good sensitivity and specificity for diagnosis of laryngopharyngeal reflux disease (LPRD). However, the correlation between RSS-12 and reflux finding score (RFS) in patients with clinical symptoms suggesting LPR has not been investigated. In this study, we examined such correlation.Patients and Methods: We conducted cohort cross sectional study over 6 months duration on 105 patients with typical gastroesophageal reflux disease (GERD) symptoms and clinical diagnosis of LPR based on RSS-12 >11. We excluded participants with medical conditions or lifestyle habits that could induce similar symptoms.Results: The prevalence of LPRD (RFS > 7) in patients with a clinical diagnosis of LPR (RSS > 11) was 14.2% (15 patients). Laryngeal findings unrelated to LPRD were present in 16 patients (15.2%). RSS-12 and duration of symptoms are strongly correlated with the existence of abnormal laryngeal findings but not with RFS.Conclusion: In patients with clinical symptoms suggesting LPR, RSS-12 can predict the existence of abnormal laryngeal findings but not the diagnosis of LPRD.