which can save a patient's life when all other medical treatments have failed, LT has emerged as a safety net to treat a variety of liver diseases. Living donor liver transplantation (LDLT) acceptance to be the only practical choice for liver transplanted patients. Early allograft dysfunction (EAD) is a well-known early clinical complication that occurs within the first week following transplantation and is thought to have a key impact on the graft and patient outcomes. Graft incapability leads to many numerals of postoperative complications, rising mortality, and hazard of organ damage. The functional estimation of transplanted liver in an early postoperative stage feature as a preference for transplant clinicians, as it mirrors the technological success of liver transplant and heavily impacts recipient results. diagnosis of early allograft dysfunction with possibility to recover with painstaking postoperative attention is urgent need. The review aims to highlight of liver transplantation and some of biochemical markers associated with early complication after liver transplantation.