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424039

Prevalence of Multidrug and Extensive drug resistance of bacterial isolates from different clinical sources in Tikrit Teaching Hospital-Iraq

Article

Last updated: 27 Apr 2025

OverviewSimilar Items

Subjects

-

Tags

Clinical microbiology

Abstract

Background: The most prevalent hospital issues globally are multidrug resistant (MDR) and extensive drug resistant (XDR) pathogens. Objective: The study aimed to identify and profile various antibiotic-resistant isolates in Tikrit Teaching Hospital. Methodology: The study at Tikrit Teaching Hospital in Iraq involved collecting 197 samples from various clinical sources and incubating them in various culture media for growth and identification. Results: Of 197 samples obtained from different clinical sources, 177 were pathogen-infected isolates. Urine was the most common sample source (71.5%), with females collecting more samples than males (90.3%). Staphylococcus aureus had a higher frequency (52%), while other bacteria had lower frequencies such as Escherichia coli, Klebsiella spp, Streptococcus spp, Pseudomonas aeroginosa and Proteus spp (26.6%, 7.3%, 12.5%, 1.1%, and 0.5%). The study assessed the susceptibility and resistance of common antimicrobial isolates, revealing a high resistance rate for all antibiotics, including Staphylococcus aureus (70.9%), Escherichia coli (77%), Klebsiella spp (79.8%), and Streptococcus spp (64.8%).The prevalence of MDR isolates was also high for Staphylococcus aureus, Escherichia coli, Klebsiella spp and Streptococcus spp (61.9%, 68%, 77% and 54.5% ) and lower for XDR (6.5%,17%, 23% and 9%). The study showed no pan-drug resistance (PDR) isolates, but a higher MDR bacteria rate (65.3%) in the studied isolates, compared with lower rates in XDR (13.9%) and non-MDR isolates (20.8%). Conclusions: The finding indicate that pathogenic bacteria have developed resistance to 22 antimicrobial agents and spread of more MDR isolates than XDR and non-MDR isolates among isolated bacteria from Tikrit Teaching Hospital.

DOI

10.21608/ejmm.2025.372019.1545

Keywords

antibiotics, Extensive drug resistant, multidrug resistant, Pan drug resistant, Pathogenic bacteria

Authors

First Name

Abdalmohaimen

Last Name

Suood

MiddleName

M.

Affiliation

Department of Biology, College of Education for Pure Science, Tikrit University , Tikrit, Iraq

Email

a.m.suood@tu.edu.iq

City

Tikrit

Orcid

0000-0002-2362-8445

First Name

Kadhim

Last Name

Kadhim

MiddleName

K.

Affiliation

Directorate of Babylon Education, Ministry of Education, Babylon, Iraq

Email

kadhim.k.kadhim@st.tu.edu.iq

City

Babylon

Orcid

-

First Name

Falah

Last Name

Dawood

MiddleName

S.

Affiliation

Department of Home Economics, College of Education for Girls, Tikrit University, Tikrit, Iraq

Email

falah.salim@tu.edu.iq

City

Tikrit

Orcid

0009-0007-0243-4530

First Name

Saade

Last Name

Jasim

MiddleName

A.

Affiliation

Medical Laboratory Techniques department, College of Health and Medical Technology, Al-maarif University, Anbar, Iraq

Email

saade.a.j@uoa.edu.iq

City

Anbar

Orcid

0009-0009-0821-5843

Volume

34

Article Issue

4

Related Issue

54773

Issue Date

2025-10-01

Receive Date

2025-04-02

Publish Date

2025-10-01

Print ISSN

1110-2179

Online ISSN

2537-0979

Link

https://ejmm.journals.ekb.eg/article_424039.html

Detail API

http://journals.ekb.eg?_action=service&article_code=424039

Order

424,039

Type

New and original researches in the field of Microbiology.

Type Code

2,038

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

Prevalence of Multidrug and Extensive drug resistance of bacterial isolates from different clinical sources in Tikrit Teaching Hospital-Iraq

Details

Type

Article

Created At

27 Apr 2025