ManageChatDiscover
394079

Harnessing Isosaponarin: A Multifaceted Bioactive and Therapeutic Potential Compound from Nature

Article

Last updated: 27 Apr 2025

OverviewSimilar Items

Subjects

-

Tags

Food Science and Technology

Abstract

Flavonoids represent a class of plant bioactive compounds renowned for their multifaceted health benefits. Among phytochemicals, polyphenols like Isosaponarin, a well-studied flavonoid, are widely distributed across various herbs and plant families, presenting notable antimicrobial and antioxidant properties. Numerous plant species harbour the Isosaponarin compound, each with distinct clinical and traditional applications. Isosaponarin-rich plants exhibit strong antimicrobial and antioxidant properties alongside noteworthy anti-hyaluronidase activity. This flavone glycoside also upregulates the mRNA gene level of type I collagen production, promoting skin health and wound healing. Studies highlight the significant effect of Isosaponarin on collagen synthesis, particularly notable in its derivation from wasabi rhizome extract and its application as a fragrance ingredient. Moreover, the research underscores its diverse biological activities, encompassing antiplatelet, anti-atopic dermatitis, and anti-tumor effects. This review aims to provide a comprehensive account of the botanical and dietary sources of Isosaponarin while delving into pivotal studies elucidating its antimicrobial and antioxidant prowess, role as an anti-hyaluronidase agent, mitigation of oxidative glutamate toxicity, and facilitation of type I collagen synthesis.

DOI

10.21608/bbj.2024.331198.1047

Keywords

Isosaponarin, multifaceted, Antimicrobial, antioxidant and anti-hyaluronidase agent

Authors

First Name

Firdos

Last Name

Kaynat

MiddleName

-

Affiliation

Department of Zoology, Faculty of Basic Sciences, University of Agriculture, Dera Ismail Khan, KPK, Pakistan

Email

balochkonain1214@gmail.com

City

Dera Ismail Khan, KPK, Pakistan

Orcid

-

First Name

Saddam

Last Name

Hussain

MiddleName

-

Affiliation

Department of Zoology, Faculty of Basic Sciences, University of Agriculture, Dera Ismail Khan, KPK, Pakistan

Email

saddamhussain883@gcuf.edu.pk

City

Dera Ismail Khan, KPK, Pakistan

Orcid

-

First Name

Basim.

Last Name

Al Sulivany

MiddleName

S. A.

Affiliation

Department of Biology, College of Science, University of Zakho, Zakho, 42002, Duhok, Kurdistan Region, Iraq

Email

basim.ahmed@uoz.edu.krd

City

-

Orcid

-

First Name

Muhammad

Last Name

Iqbal

MiddleName

J

Affiliation

Department of Zoology, Faculty of Life Sciences, Government College University Faisalabad, Punjab, Pakistan.

Email

-

City

-

Orcid

-

First Name

Muhammad

Last Name

Owais

MiddleName

-

Affiliation

Department of Zoology, Emerson University Multan, Punjab, Pakistan

Email

owaisgulmuhammad@gmail.com

City

-

Orcid

-

First Name

Paracha

Last Name

Rizwan

MiddleName

N

Affiliation

Department of Chemistry, Faculty of Science, Thal University Bhakkar, Punjab, Pakistan

Email

rizwanparacha@gmail.com

City

Punjab, Pakistan

Orcid

-

First Name

Rana

Last Name

Fazal

MiddleName

M.

Affiliation

Department of Zoology, Ghazi University, Dera Ghazi Khan, Punjab, Pakistan.

Email

rfazal@gudgk.edu.pk

City

Punjab/Pakistan

Orcid

-

Volume

3

Article Issue

2

Related Issue

52204

Issue Date

2025-07-01

Receive Date

2024-11-09

Publish Date

2025-07-01

Page Start

1

Page End

12

Print ISSN

2974-4334

Online ISSN

2974-4342

Article File

BBJ_Volume 3_Issue 2_Pages 1-12.pdf

PDF . 877.7kB

Link

https://bbj.journals.ekb.eg/article_394079.html

Detail API

http://journals.ekb.eg?_action=service&article_code=394079

Order

394,079

Type

Review Articles

Type Code

2,846

Publication Type

Journal

Publication Title

Biological and Biomedical Journal

Publication Link

https://bbj.journals.ekb.eg/

MainTitle

Harnessing Isosaponarin: A Multifaceted Bioactive and Therapeutic Potential Compound from Nature

Details

Type

Article

Created At

27 Apr 2025