Early mobilization (EM) refers to the implementation of a physiotherapy program (passive mobilization, active mobilization and respiratory muscle training) or new mobilization techniques .The study aimed to explore the barriers to early mobilization of patients admitted to the intensive care unit (ICU) in Omdurman teaching hospital. Khartoum state. 2025 ,and find association of demographic data and these barriers. Material and methods: descriptive cross sectional hospital based study .66 nurses selected by systematic random sampling who enrolled in the study who worked in ICU . majorityof them were females with BSC certificates . The survey addressed patient-related barriers, structural related barriers, cultural related barriers, and process-related barriers. Results: majority of nurses reported that Respiratory instability/distress, ventilator asynchrony 10 (15.2%), Limited staff, Lack of early mobility program/protocol (e.g., no routine delivery of Physiotherapy), limited guidelines, no eligibility criteria (54.3%), Lack of planning and coordination (60.9%), Inadequate staff training 19 (28.9%) represented major barriers for EM. Conclusion: Early mobilization protocols can be implemented in ICUs after adequate addressing of potential barriers that can face healthcare workers, prepare the ICU environment with equipment and trained personnel. We suggest that successful implementation programmers of early mobilization, significant culture change is required and relies on involvement from all members of the multidisciplinary team. And having access to the right tools, training and processes is key. This study aimed to explore Barriers to Early Mobilization of Patients Admitted to the Intensive Care Unit at Omdurman Teaching Hospital, Khartoum State 2025