This study investigated the population density of aphids and their associated predators during two wheat seasons in Qutour, Gharbia, Egypt, along with the effect of weather factors (temperature and humidity). Two sampling methods were used: visual inspection and sweep net collection. Results obtained indicated that aphid densities were nearly similar in both seasons. Rhopalosiphum padi was the first species to appear, peaking at 380 individuals per leaf in late February before declining. There was no significant difference between R. padi and R. maidis populations, whereas a strong positive correlation was observed between Sitobion avenae, Diuraphis noxia, and their predators. In the 2022 season, temperature showed a significant negative correlation with R. maidis, R. padi, and D. noxia, while its correlation with S. avenae populations was significant. No significant correlation was found between Schizaphis graminum and predator populations. Relative humidity had a significant positive correlation with all aphid species except S. avenae. Predator populations were not significantly correlated with temperature. In the 2023 season, temperature negatively correlated with R. maidis and R. padi, while no significant correlations were detected for other species and their predators. These findings highlight the influence of weather factors on aphid and predator populations and their interaction, providing insights for pest management strategies in wheat crops.