Background: Fluoride toothpaste is widely used to prevent and limit caries. Exploring alternative formulations that offer additional benefits could be valuable. This study aimed to compare the effects of experimental bioactive glass (BioMin) with commercial fluoridated toothpaste on the sound primary teeth demineralized in-vitro.
Methods: Sixty exfoliated anterior primary teeth were split into three equal groups All samples were exposed to a demineralization solution for a period of 96 hours., followed by separate remineralization for each group: Group I (artificial saliva), Group II (fluoridated toothpaste), and Group III (BioMin toothpaste) for 15 days. The outermost microhardness of each sample was evaluated via a Vickers microhardness apparatus, and the lesion depth was determined via a polarised light microscope and ImageJ 1.46r software. Data was evaluated using one-way ANOVA and Tukey's HSD Test (honestly significant difference)
Results: compared with the controls (P < 0.001) and fluoridated toothpaste (P < 0.05), the Biomin toothpaste demonstrated significantly superior results in terms of microhardness and lesion depth. In contrast, the fluoridated toothpaste led to a statistically insignificant rise in microhardness and a reduction in lesion depth (P = 0.52 and 0.78 respectively). Qualitative assessment showed that both agents contributed to reducing lesion depth.
Conclusion: The new bioactive glass paste (BioMin® F) had a more significant effect than fluoridated toothpaste in treating artificial caries caused by enamel demineralization.