Three hundred and fifty-seven (357) unsexed broiler chicks (Arbor Acer), that were one day old, were weighed and split into seven equal experimental groups, each with three replicates (17 chicks per replicate), to examine the effects of supplementing mixture enzymes of xylanase plus glucanase as natugrain® TS (NE) to broiler diets containing different levels of rice bran (RB) on the growth performance, nutrient digestibility's and carcass traits, as well as economic efficiency during the fattening period (42 days). The groups were arranged as follows: the first fed a control diet (NC) without RB and non-supplemented with NE and set as a negative control group, while the second and third were fed an NC diet plus 1.0 and 2.0 g NE/kg, respectively; the fourth and fifth contained 7.5% RB plus 1.0 and 2.0 g NE/kg, respectively, while the sixth and seventh groups were fed a diet containing 15.0% RB plus 1.0 and 2.0 g NE/kg, respectively, during the starter, grower and finisher periods. The obtained results showed that all studied growth traits were significantly (P<0.05) improved by feeding the RB diet as compared with the control. Nutrient digestion and feeding value were significantly lowered by using RB in broiler diet. Relative weights of both eviscerated carcass and total edible parts were significantly (P<0.05) improved by using RB in broiler diet at 40 days of age. Both net revenue and economic efficiency were significantly higher by feeding RB diet plus NE addition at 40 days of age. From the obtained results, feeding dietary rice bran (up to 15.0%) with a mixture of enzymes of xylanase and glucanase (1.0 or 2.0 g/kg diet) could be used to improve growth performance, carcass traits and nutrient digestibility coefficients, as well as economic efficiency for broiler chicks during the fattening period.