B
Background: Patient safety is one of the nations' most pressing health care challenges. Pediatric nurses have an important role in understanding and applying the safety standard precautions goals for neonatal safety to minimize the occurrence of hazards and errors in nursing care. Aim: To explore the effect of the nursing intervention program on safety standards precautions on the performance of nurses in neonatal intensive care units.  Design: A quasi-experimental one-group (pre-post) assessment research design was used in conducting this study. Subjects: A Convenience sampling consisted of 70 nurses that were working in neonatal intensive care units at four hospitals affiliated to the Universal Health Insurance Authority (UHIA) in port said governorate regardless their characteristics. Tools: Two main tools were used to collect data in this study: The observational Checklist and a self-administer questionnaire were used to gather the data. Results: more than three quarters of the studied nurses (75.7%) had satisfactory total score of knowledge about safety standards precautions in pre intervention phase, and increased to 95.7% in post intervention phase. Also, improvement in the overall practices of the studied nurses throughout the program phases from 81.4% to 97.1% in post intervention phase. Conclusion: There was improvement of nurses' total score of knowledge and their overall practices after program implementation. Recommendations: Continuous health teaching and training programs for recently pediatric nurses that emphasize the significance of enhancing their implementation of safety standard precautions in neonatal intensive care units.