394104

Neonatal Cord Blood PH versus Eucapnic PH as a Predictor for NICU Admission

Article

Last updated: 09 Apr 2025

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Abstract

Background: For clinicians to determine the possibility for neonate brain damage and guide therapeutic decisions to avoid long-term complications, as cerebral palsy involving umbilical artery cord PH, base deficit, and lactic acid, the majority of biomarkers that are utilized for assessing fetal wellbeing, neonatal metabolic acidosis, and its associated complications in newborns are inaccurate and non-specific. On the other hand, the PHeucap demonstrates that it is the best biomarker and predictor for newborn metabolic acidosis and the obstacles that are associated with it. Aim: To evaluate the value of neonatal cord eucapnic PH in prediction of neonatal intensive care unit (NICU) admission in newborn subjected to perinatal asphyxia. Patients and methods: This prospective cohort investigation has been performed conducted on 40 newborns delivered at Benha university in Neonatal intensive care unit (NICU), from 1 March 2023 till 1 March 2024 who subjected to perinatal asphyxia and cord blood pH and eucapnic pH were measured and correlated with parameters of morbidity and mortality. Results: ROC analysis (Receiver operation Curve) showed that eucapnic PH had best prediction for NICU admission with sensitivity (90.91%) and specificity (58.62%) at cut-off point(7.03), while umbilical artery (UA)cord PH had sensitivity (63.64%) and specificity (55.85%)at cut-off point(6.85). a significant positive correlation has been detected between UA cord and pH euc-n and between pH euc-n and UAco2 with(r=0.369, P=0.019). (r=0.789, P

DOI

10.21608/bmfj.2024.324769.2214

Keywords

Eucapnic PH, neonatal cord blood pH, NICU

Authors

First Name

Rasha

Last Name

Zakaria

MiddleName

Mohammed

Affiliation

Department of Pediatrics, Faculty of Medicine Benha University

Email

rasha.radwan@fmed.bu.edu.eg

City

-

Orcid

-

First Name

Mohammed

Last Name

El Bakry

MiddleName

Mostafa

Affiliation

Department of Pediatrics and Neonatology Medicine Dept, Faculty of medicine, Benha University, Egypt

Email

mohamed.albakry@fmed.bu.edu.eg

City

-

Orcid

-

First Name

Zeinab

Last Name

Ahmed Elsayed

MiddleName

Elsayed

Affiliation

Department of Pediatrics and neonatology, Faculty of Medicine - Benha University

Email

pedia.zeinab@gmail.com

City

-

Orcid

-

First Name

Eman

Last Name

G. Abdelrahman

MiddleName

-

Affiliation

department of Pediatrics Cardiology, Faculty of Medicine - Benha University

Email

eman.gamal@fmed.bu.edu.eg

City

-

Orcid

-

Volume

42

Article Issue

4

Related Issue

54800

Issue Date

2025-04-01

Receive Date

2024-09-29

Publish Date

2025-04-01

Page Start

382

Page End

390

Print ISSN

1110-208X

Online ISSN

2357-0016

Link

https://bmfj.journals.ekb.eg/article_394104.html

Detail API

http://journals.ekb.eg?_action=service&article_code=394104

Order

5

Type

Original Article

Type Code

787

Publication Type

Journal

Publication Title

Benha Medical Journal

Publication Link

https://bmfj.journals.ekb.eg/

MainTitle

Neonatal Cord Blood PH versus Eucapnic PH as a Predictor for NICU Admission

Details

Type

Article

Created At

09 Apr 2025