419908

Microfragmented Adipose Tissue Injection Compared to Hyaluronic Acid for Treatment of Temporomandibular Joint Osteoarthritis. (A Randomized Clinical Trail)

Article

Last updated: 09 Apr 2025

Subjects

-

Tags

Oral and Maxillofacial Surgery

Abstract

Abstract:
Objective: This study aimed to evaluate the effectiveness of standard hyaluronic acid (HA) injections following arthrocentesis compared to micro-fragmented adipose tissue injection derived from the buccal fat pad.
Methods: 26 patients with temporomandibular joint disorders were randomly assigned to two groups: Group A; which received HA injections, and Group B; which received adipose tissue injections. Pain levels were assessed using the visual analog scale, and function was measured by maximum interincisal opening at five intervals: before the procedure, after day one, 1 week, 1 month, and finally after 3 months post-procedure.
Results: Both groups exhibited significant improvements and positive effects on pain relief, quality of life, and functional mouth opening compared to their baseline measurements.
Conclusion: Initial and final results suggest that micro-fragmented adipose tissue injections may offer enhanced benefits in terms of pain reduction, improved life quality, and functional improvement compared to the conventional Hyaluronic acid (HA) treatment.

DOI

10.21608/edj.2025.356964.3365

Keywords

TMJ disorders, Adipose- tissue injection, Pain Relief

Authors

First Name

nahla

Last Name

awadallah

MiddleName

mahmoud

Affiliation

Lecturer at Oral and Maxillofacial Department Faculty of Dentistry, Cairo University

Email

nahla.awad@dentistry.cu.edu.eg

City

-

Orcid

0000000262872299

First Name

mutaz

Last Name

alsayed

MiddleName

al khair

Affiliation

Professor, Oral and Maxillofacial Surgery, Faculty of Dentistry, Cairo University.

Email

mutaz.elsayed@dentistry.cu.edu.eg

City

cairo

Orcid

0009-0008-8777-0935

First Name

hesham

Last Name

eLhawary.

MiddleName

Alsayed

Affiliation

Msc Student, Oral and Maxillofacial Department, Faculty of Dentistry, Cairo University

Email

hesham.elhawary@dentistry.cu.edu.eg

City

cairo

Orcid

0000-0002-7052-3283

Volume

71

Article Issue

2

Related Issue

54788

Issue Date

2025-04-01

Receive Date

2025-02-03

Publish Date

2025-04-01

Page Start

1,243

Page End

1,250

Print ISSN

0070-9484

Online ISSN

2090-2360

Link

https://edj.journals.ekb.eg/article_419908.html

Detail API

http://journals.ekb.eg?_action=service&article_code=419908

Order

419,908

Type

Original Article

Type Code

254

Publication Type

Journal

Publication Title

Egyptian Dental Journal

Publication Link

https://edj.journals.ekb.eg/

MainTitle

Microfragmented Adipose Tissue Injection Compared to Hyaluronic Acid for Treatment of Temporomandibular Joint Osteoarthritis. (A Randomized Clinical Trail)

Details

Type

Article

Created At

09 Apr 2025