Diabetes mellitus is a metabolic illness. Clinical manifestations include blood lipid and protein abnormalities, persistent hyperglycemia, and other conditions that have been widely shown to be associated with many consequences that severely lower the quality of life. The primary cause of lower extremity amputations and the development of chronic wounds is impaired wound healing. Diabetic foot ulcers are thought to be the secondary cause of 85% of foot amputations. The purpose of this study was to compare the levels of HDL, VLDL, triglycerides, cholesterol, and some biochemical markers, such as FBG and HbA1c, between healthy people and those with diabetes mellitus. Additionally, it seeks to identify a connection between a patient's elevated lipid profile and diabetes mellitus. Methodology: Look into a case-control study that was conducted for a period starting from March/2023 to May/2023 in Baghdad teaching hospital / medical city / Baghdad / Iraq. It was based on a clinical examination, the total number of participants were 50 subjects; they were divided into two groups: 30 subjects were patients with diabetes mellitus and 20 subjects we healthy control subject, all were subjected to laboratory tests: HBA1C, FBG, Cholesterol, Triglyceride, HDL, LDL and VLDL. From 50 included subjects, 20 were male and 40 female. Findings demonstrated that there were significant differences among the studied groups regarding age and gender. There were significant differences in HBA1c, FBG, Cholesterol, Triglyceride, HDL, and VLDL among the two studied groups. Whereas no significant differences were found in LDL among the two studied groups.
Key words: Diabetes mellitus, HDL, LDL, Triglyceride.