Background: Active learning (AL) strategies engage students in the learning process and encourage them to reflect on their learning. Aim: The aim of the current study was to assess perception of active learning among nursing students at Al Baha University. Design: Descriptive cross-sectional research design was adopted to conduct this study. Setting: This study was conducted at Al-Baha University, Faculty of Applied Medical Sciences, Nursing Department. Sample: Convenience sampling technique was employed to select 89 students who fulfill the inclusion criteria. Instruments: An online questionnaire was used to assess students' perception of active learning. This instrument consists of three dimensions; benefits of active learning, factors affecting active learning, and barriers to active learning. Results: Active learning was beneficial from study subjects' perspectives. The highest percentage of agreement was that active learning boosts self-confidence amongst the students, increases teacher-student interaction and develops more interest in studying. Furthermore, students agree on almost all factors influencing active learning. Regarding barriers to active learning, most of students considered large group of students in the class as a major barrier for active learning. Recommendation: The active learning as teaching and learning strategy should be adopted in teaching students in nursing program, there should be motivation in the form of extra marks and recognition for students who are active participants in the active learning process.