Background: Chronic obstructive pulmonary disease is a chronic respiratory diseases pose a high burden of morbidity and mortality on health systems and patients globally. Clinical Pathways encourage the application of evidence-based practice, improve clinical practices by reducing risk and variation in healthcare delivery, and get rid of redundancies by using a standard approach to clinical management. Aim: Measure the effect of implementing clinical pathway on health status and functional capacity of elderly patients with chronic obstructive pulmonary disease. Research design: A quasi experimental research design was utilized. Method: Sixty two chronic obstructive pulmonary disease elderly patients who were attending the Mansoura University Hospital's chest medicine department were included in the purposeful sample. The individuals were split equally into two groups: study group (n=31) who received clinical pathway protocol, and control group (n=31) who received only routine care. Results: Elderly patients in the study group had significantly improved health status on discharge than the control group with mean 15.03±5.74 and 23.77±6.15 for the study group and control group respectively. The mean distance achieved by study group on admission was 245.48±54.70 meter and it improved on discharge to 283.22±55.46 meter with a significant difference (p <0.001). Conclusion: Clinical pathway is effective tool in improving health status, functional capacity of elderly patients with chronic obstructive pulmonary disease. Recommendation: Incorporating the chronic obstructive pulmonary disease clinical pathway into the plan of care of elderly chronic obstructive pulmonary disease patients to replace the conventional nursing care plan for better quality of care.