Background: Job demands among nurses can lead to health problems such as low productivity, an increase in nurses' errors, an increase in expenses, and decreased retention, which may have an influence on nurses' mindfulness. Also, delayed task completion raises the chance of errors, which ultimately affects the well-being of patients and leads to missed nursing care. Aim: To investigate nursing job demands and mindfulness and it`s relationship with missed nursing care at Meniat El Nasr Central Hospital. Design: A descriptive-correlated study design was used to perform the study. Methods: There were three tools utilized: the job demand scale, mindful attention awareness scales, and missed nursing care scales. Results: The majority of studied nurses (57.2% )had ahigh levels of job demand; and more than half of them had a high level of mindfulness; and more than one third had a low level of missed nursing care. Conclusion: There is a highly statistically significant negative relationship between job demands and mindfulness. Also, there is a highly statistically significant positive relationship between job demands and missed nursing care and there is a highly statistically significant negative relationship between job mindfulness and missed nursing care. Recommendations: Establish an environment that lowers excessive job demands. Nurse managers have to foster a productive workplace with adequate staffing and supplies, as well as encourage collaborative work, to avoid missed nursing care. Additionally, a clear communication and feedback mechanism regarding errors should be maintained.