Background: Asthma is a major and prevalent worldwide health issue that can lead to major health complications in older adults, when left untreated. Aim: Measure the effect of buteyko breathing exercise on pulmonary functions tests and quality of life in asthmatic elderly patients. Setting: This study was done at chest disease department affiliated to Mansoura University Hospital. Subjects: A purposively selection of 80 elderly patients divided to two groups (40) for each group attending the previous mentioned setting who fulfilled requirements for inclusion. Tools: Three tools were used in this study; Demographic and Health related Data Structured Interview Schedule, Asthma Control Questionnaire 5 (ACQ-5) and Buteyko Breathing Technique Observational Checklist. Results: Asthma control did not show any statistically significant variations between the buteyko and control groups prior to the training program's implementation (P= 0.879), but there were statistically significant variations between the two groups three and six months after the training sessions (P= 0.024 and P= 0.002, respectively). There was a positive significant correlation between total practice score and asthma control. Conclusion: Buteyko breathing exercise can be used safely for elderly patients with asthma. The implementation of buteyko breathing exercise training had positive effects in improving asthma control. Recommendation: Educational programs development and training for all elderly patients in all health care hospitals to increase their benefits from the effect of Buteyko exercise.