Abstract
Background: H. Pylori is considered a causative agent of chronic gastritis, peptic ulcer and non-cardia adenocarcinoma of the stomach. Some studies suggest an association and possible causality of H. pylori infection in some dermatological diseases. The aim of the work was to assess the frequency of dermatological diseases in patients with H. Pylori infection. Methods: This was an observational cross-sectional study, carried out at Aswan University Hospital. 200 patients infected with H. Pylori, diagnosed by stool antigen test, were selected for dermatological evaluation to detect the presence of dermatological diseases and the effect of H. Pylori treatment on these diseases. Re-testing was performed to confirm successful eradication. Results: Only 23 patients (11.5%) had skin manifestations; the most frequent was generalized itching (34.8%), followed by chronic idiopathic urticaria. The least frequent was Lichen planus with Vitiligo (4.3%). Of whom, thirteen patients (56.5%) responded well to treatment while ten patients (43.5%) didn't respond to treatment. Conclusion: Nearly most of the H. Pylori infected patients (88.5%) did not suffer from any skin manifestations and there is no significant causation between dermatological diseases and H. Pylori infection but maybe there is an association, as evident by improvement of dermatological diseases after H. Pylori eradication.
Keywords: Dermatological diseases, H. Pylori, dermatitis.