Aim: compare the post- operative pain associated with sealer-based obturation technique (SBO) ‎using bioceramic sealer and a (CWC) obturation technique with a resin-based sealer. Materials and methods: two-‎arm randomized clinical trial with 2 parallel groups 20 patients each, after shaping the canals to a ‎minimum dimension of 30/.04, except for a single middle mesial canal, which was shaped to 25/.04 ‎patients randomly allocated into two groups based on the obturation material used. To ensure patient ‎privacy, each name was replaced with a case number. Patients documented their pain on a 0–10 (VAS) at: ‎‎4 hours, one day, and two days after canal obturation. The pain score was recorded at its highest value ‎three successive time points selected and then sorted. Data were presented as mean, standard deviation ‎‎(SD), median, and interquartile range (IQR) values. They were analyzed by Mann-Whitney U and signed ‎rank tests, respectively. The significance level was set at p<0.05 within all tests. Results: The two groups ‎showed no significant difference. With higher pain score for CWC group. Conclusion: Within the ‎restrictions of this study, both CWC with AH+ sealer with and sealer based obturation with Bio-C sealer ‎showed no significant pain level.‎