Purpose: To qualify prognostic factors affecting the success rate of 3 different surgical techniques to treat patients with PCG.
Patients and Methods: This retrospective cohort study included 149 eyes of 85 children diagnosed with PCG who underwent single site trabeculotomy, combined trabeculotomy trabeculectomy or double site metal probe trabeculotomy. Logistic regression analysis was performed to detect correlations between the success rate (at 24 months postoperatively) and preoperative IOP, corneal diameter, axial length, age of onset of the disease, consanguinity, surgical technique and postoperative corneal and axial length growth.
Results: There were no correlations between success rate and sex, laterality, consanguinity, preoperative corneal diameter, axial length. Age of onset less than (2.00 ± 1.954) months was statistically associated with failure. Preoperative IOP higher than (30.37 ± 5.614) mmHg was associated with failure. Complete success was 100% in mild, 86.76 in moderate and 64.86% in severe cases, thus, severity had an association with failure. In severe cases, complete success was 90% in single site trabeculotomy, 47.83% in CTT and 88.23% in double site trabeculotomy group. Postoperative hypotony occured in 68.2% of the failed eyes and 34.9% of successful eyes, and was statistically associated with failure. Postoperative accelerated corneal diameter and axial length growth was statistically associated with failure.
Conclusion: Early onset of glaucoma, high preoperative IOP, glaucoma severity and postoperative early hypotony can be correlated with failure. Angle surgery whether single or double site trabeculotomy had higher success than combined trabeculotomy trabeculectomy.