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417163

The role of Human Papillomavirus and Surrogate Immune Markers in Urinary Bladder Cancer in Mansoura Urology and Nephrology Centre

Article

Last updated: 29 Mar 2025

OverviewSimilar Items

Subjects

-

Tags

Pathogenicity and virulence

Abstract

Bladder cancer ranks 13th globally in terms of cancer-related deaths and is the 10th most prevalent type of cancer overall. Smoking and urinary tract infections, such as schistosomiasis, are the most reported risk factors for bladder cancer. An association between infection either bacterial or viral with cancer was reported. Human papillomavirus (HPV), Herpes simplex virus, BK virus, Bovine leukemia virus and Human immunodeficiency virus are linked with cancer development. Viruses cause about 15–20% of all types of cancers, but 10 percent are due to HPV. HPV, is DNA virus, infects the cutaneous or mucosal epithelium and belongs to papillomaviruses family. Immune. Studies have shown that immune-related markers play an important role in the diagnosis, prognosis assessment and treatment of bladder cancer. In addition, the detection of immune-related markers can also be used to evaluate the efficacy of immunotherapy and predict the treatment response of patients.  HNPs 1–3 are subtypes of α-defensins, proteins that aid in the recruitment of leukocytes and might contribute to metastasis.

DOI

10.21608/ejmm.2025.365544.1504

Keywords

Keywords: Human papilloma virus, Immunological cells, Bladder cancer, HPV

Authors

First Name

Basma

Last Name

Omar

MiddleName

A.

Affiliation

Department of Medical Microbiology and Immunology, Urology and Nephrology Centre, Mansoura University

Email

basmaomar90@outlook.com

City

-

Orcid

-

First Name

Dalia

Last Name

Moemen

MiddleName

M.

Affiliation

Department of Medical Microbiology and Immunology, Mansoura University

Email

dr_daliamoemen@yahoo.com

City

mansoura

Orcid

0000-0002-4103-3840

First Name

Bassem

Last Name

Wadie

MiddleName

S.

Affiliation

Urology and Nephrology Center, Mansoura University

Email

bwadie@aol.com

City

Mansoura

Orcid

-

First Name

Enas

Last Name

Hammad

MiddleName

A.

Affiliation

Department of Medical Microbiology and Immunology, Mansoura University

Email

enashammad@yahoo.com

City

Mansoura

Orcid

-

First Name

Medhat

Last Name

El-Daker

MiddleName

A.

Affiliation

Department of Medical Microbiology and Immunology, Mansoura University

Email

meldaker@yahoo.com

City

Mansoura

Orcid

-

Volume

34

Article Issue

3

Related Issue

53640

Issue Date

2025-07-01

Receive Date

2025-03-04

Publish Date

2025-07-01

Print ISSN

1110-2179

Online ISSN

2537-0979

Link

https://ejmm.journals.ekb.eg/article_417163.html

Detail API

http://journals.ekb.eg?_action=service&article_code=417163

Order

417,163

Type

Review articles

Type Code

2,039

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

The role of Human Papillomavirus and Surrogate Immune Markers in Urinary Bladder Cancer in Mansoura Urology and Nephrology Centre

Details

Type

Article

Created At

29 Mar 2025