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419587

Correlation between Hypertensive Retinopathy and Sever-ity of Coronary Artery Disease in Hypertensive Patients.

Article

Last updated: 27 Apr 2025

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Tags

Clinical Research (Medical)

Abstract

Background: Hypertensive retinopathy (HR) reflects systemic microvascular damage, but its role as an independent risk factor of coronary artery disease (CAD) severity remains underexplored. Aim: this research aims to investigate the association between degree of hypertensive retinopathy (HR) and retinal arteriosclerosis (AS) with CAD severity in hypertensive patients. Methods: In this cross-sectional study, 100 hypertensive patients (aged 35–75 years) with angina and confirmed CAD underwent coronary angiography and assessment of the intensity of CAD was assessed by Gensini score and a correlation with fundoscopic examination to assess the severity of hypertensive retinopathy and retinal arteriosclerosis by using Scheie classification was done. Statistical testing included Spearman's correlation and multivariate linear regression. Results: hypertensive retinopathy and retinal arteriosclerosis stages showed strong positive correlations with CAD severity (rho = 0.72 and 0.65, respectively; p < 0.001). In multivariate analysis, each hypertensive retinopathy stage increases independently predicted an 8.4-point rise in Gensini score (95% CI: 6.2–10.6; p < 0.001), outperforming traditional risk factors (age, smoking, cholesterol). Conclusion: Hypertensive retinopathy is a strong, independent predictor of CAD severity. Retinal examination may enhance risk stratification in hypertensive patients, offering a non-invasive tool for early CAD detection.

DOI

10.21608/scumj.2025.419587

Keywords

Hypertensive retinopathy, Coronary Artery Disease, Gensini score, arteriosclerosis

Authors

First Name

Mohammed

Last Name

El Merry

MiddleName

Ahmed

Affiliation

Cardiology department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

m25merry@gmail.com

City

-

Orcid

0009-0002-4499-1611

First Name

Hesham

Last Name

Ali

MiddleName

Hegazy

Affiliation

Cardiology department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

dochegazy@yahoo.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Yehia

MiddleName

Khaled

Affiliation

Cardiology department, Al Ahrar Teaching Hospital, Zagazig, Egypt

Email

-

City

-

Orcid

-

First Name

Mohamed

Last Name

Saber

MiddleName

Yousef

Affiliation

Cardiology department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

mohamedyoussef@yahoo.com

City

-

Orcid

-

Volume

28

Article Issue

2

Related Issue

53275

Issue Date

2025-02-01

Publish Date

2025-02-17

Page Start

6

Page End

12

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 28_Issue 2_Pages 6-12.pdf

PDF . 376.4kB

Link

https://scumj.journals.ekb.eg/article_419587.html

Detail API

http://journals.ekb.eg?_action=service&article_code=419587

Order

2

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

Correlation between Hypertensive Retinopathy and Sever-ity of Coronary Artery Disease in Hypertensive Patients.

Details

Type

Article

Created At

29 Mar 2025