Background: Diabetes Conversation Maps (DCM) are considered as useful tools for the education of diabetes patients. DCM is interactive tools containing pictorial messages and directions designed to educate patients with diabetes and their family members. Aim: This study aimed to evaluate the effect of diabetes conversation maps on knowledge and self- management for patients with type 2 diabetes. Design: A quasi-experimental research design was used in this study. Setting: The study was conducted at outpatient clinics; Badr hospital in Helwan University. Sample: A purposive sample of 100 patients, from total 135 patients was attended in the above mentioned setting in the previous year. Tools: Two tools were used in this study: Structured interviewing questionnaire which includes patient's demographic characteristics, and patients' level of knowledge regarding diabetes mellitus and diabetes self-management questionnaire. Results: Demonstrates that, 2% of the studied patients had satisfactory total knowledge regarding diabetes mellitus during pre-implementation and improved post implementation of diabetes conversation map to become 82%. Also, 6% of the studied patients had good total self-management practices pre-implementation and improved to become 79% of them post implementation of diabetes conversation map. Conclusion: There was a statistically significant improvement in patients' knowledge and self-management practices regarding to diabetes mellitus post implementation of diabetes conversation map and comparing to pre implementation. Recommendations: Increase public awareness about diabetes conversation maps in improving knowledge and self-management of diabetic patients.