Background: Psoriasis is a chronic condition that significantly impacts many facets of life and causes patients to experience several psychosocial issues that impair their ability to adjust. This study aimed to assess psychosocial problems and adjustment patterns among patients with psoriasis. This study utilized a descriptive-correlational design. The dermatology department and outpatient clinic at Benha University Hospital in Benha City, Qalyubia Governorate, served as the study's setting. Sample: a convenient sample of 100 psoriasis patients was selected from the previous setting. Instruments: (1): A structured Interviewing Questionnaire Sheet, (11): Psychosocial Problems scale and (111): adjustment patterns scale. Results reflected that less than half of studied patients had moderate level of psychosocial problems. Also, more than half of the studied patients had low level of adjustment patterns.  The study concluded that there was a highly statistically significant negative correlation between mean scores of total levels of psychosocial problems and adjustment patterns among the studied patients. According to results researchers Recommended conduction of stress management and assertiveness training program for all patients with psoriasis to relieve their psychosocial problems and enhance adjustment patterns.