Background: Meningioma is a main frequent tumor of the central nervous system, which arises from arachnoid cap cells and forms approximately 30% of overall main adults' intracranial tumors. The aim of the research was to appraise the impact of Nursing Educational Strategies Regarding Complications Post Meningioma on Nurses Knowledge and Practices. Research Design: This study utilized design to investigate the research objectives. Setting: The research was performed in Department of Neurosurgery at the Zagazig Surgery Hospital. Sample: The sample consisted of all the 35 nurses employed at the Surgery hospital in Zagazig. Tools: Two tools were utilized to collect the Data: nurse knowledge questionnaire, and a practices observational checklist. Results: Revealed that before the nursing program; only 22.5 % of the surveyed nurses possessed a good overall knowledge, however after the nursing strategies intervention; good total knowledge score increased to 62.9%. Before nursing strategies intervention, 68.6% of the surveyed nurses exhibited inadequate practice, however after nursing strategies intervention, satisfactory practice score increased to 74.3. Conclusion: The findings underscore the nursing strategies effectiveness in enhancing nurses' knowledge, and practices toward complications post meningioma. Recommendations: Replication of the present research on a bigger group of nurses from various hospitals.