The present study aimed to investigate the nutritional value of red radish roots, red cabbage leaves, and turnip roots and their therapeutic effect in alleviating some side effects in rats with fibromyalgia. Chemical composition, mineral, and vitamin contents were determined. The biological experiment proceeded on forty rats divided into eight groups (5 rats each), the first group was fed a basal diet only, and the remaining seven groups were injected with reserpine to induce fibromyalgia; one of them continued feeding on the basal diet (positive control). Three injured groups received the powder of red radish roots, red cabbage leaves, and turnip roots in the diet, while the other three groups received their ethanolic extracts orally. At the end of the experiment, blood samples were collected for analysis. The results revealed that the treated groups with red radish roots, red cabbage leaves, and turnip root extracts revealed significant decreases in their blood TC, TG, and LDL-c levels as well as  ALT and AST levels and an increase in serum HDL-c and albumin levels significantly compared to the positive control. Significant reduction in serum creatinine, urea, and blood sugar levels was observed in the treated groups compared to the positive control group. However, the ethanolic extract of red radish roots, red cabbage leaves, and turnip roots was more effective than the powder in reducing the side effects of reserpine-induced fibromyalgia in rats. Thus, these plants are recommended for patients with fibromyalgia.