A pot experiment was conducted to test the NP-enriched sawdust for replenishment the reduction amounts of mineral fertilizers added to maize plants grown in three different soils. For ensure this aim, specific objectives were investigated to characterize the physical and chemical properties of sawdust nanoparticles (nSD) and the collected bulk sawdust (bSD); to compare the effect of NP-enriched bulk or nano-sawdust supplemented with mineral fertilizer with the conventional mineral fertilization on maize dry matter grown on different soil types. To achieve these objectives, nanoparticles of sawdust were produced, characterized and saturated with 160 mg per liter ammonium and phosphate solutions. The results revealed that the co-application of mineral fertilizers and NP-enriched bSD or nSD significantly increased dry matter production of maize plants grown on the three studied soils. The highest biomass production of maize was noticed at 0.75 mineral co-applied with 0.25 bSD or 0.025 nSD in all studied soils. More biomass production was produced at the different application rates of nSD when it is applied individually or co-applied with mineral fertilizers. The polynomial quadratic model was successfully described the relationship between dry matter production of maize grown on the three studied soils and fertilizer type application rates. The co-application effects of mineral fertilizers and NP-enriched bSD or nSD on element concentrations of maize plants grown on the three studied soils indicated to significant differences in element concentrations of maize as affected by mineral co-applied with bSD or nSD application rates. Also, the highest element concentrations of maize was noticed at 0.75 mineral co-applied with 0.25 bSD or 0.025 nSD in all studied soils. It can be concluded that the more dry matter production and element concentrations at different rates of studied sawdust nanoparticles when it is applied individually or co-applied with mineral fertilizers may due to the entry of nanoparticles through the cell wall. Moreover, bSD and nSD containing more organic carbon and other constitutes that increase the availability of studied elements.