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355402

Study of the Relation between Primary Open Angle ‎Glaucoma and Serum Lipid Levels

Article

Last updated: 09 Mar 2025

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Abstract

Background: Glaucoma is identified as a progressively worsening optic neuropathy triggered by multiple factors and it is acknowledged as the foremost irreversible cause of blindness internationally. Emerging epidemiological inquiries indicate a potential association between elevated lipid levels and glaucoma, yet these findings present a dichotomy. Our research endeavor was aimed at delineating the connection between POAG and the levels of serum lipids.
Methods: This cross-sectional, observational clinical investigation was conducted on 50 subjects in Ophthalmology Department in Benha University Hospital. Participants were classified into 25 control group and 25 POAG cases. All subjects underwent detailed history taking, best corrected visual acuity (BCVA) using Snellen's chart, Pupillary reaction, Anterior segment examination using slit lamp biomicroscopy, IOP measurement using slit lamp mounted Goldman applanation tonometer and assessment of serum lipid levels.
Results: odd of severe POAG was 1.081 times greater for higher TC level (95%CI 1.00-1.168), 1.124 times greater for higher TG level (95%CI 1.012-1.246), and 0.569 times greater for higher VLDL level (95%CI 0.356-0.910). Univariate analysis shows that TC, TG, LDL and risk ratio I were the predictors of POAG, while multivariate analysis showed that only VLDL was the predictor of POAG.
Conclusions: Our findings imply that dyslipidemia, characterized by high cholesterol, serum triglycerides, and LDL levels is linked to a higher risk of POAG. This research lays the groundwork for further studies on reducing dyslipidemia's impact on POAG prevalence and the effect of statin use in dyslipidemia on POAG progression.

DOI

10.21608/bmfj.2024.284229.2063

Keywords

Primary Open Angle ‎Glaucoma, Serum Lipid Levels, IOP, severity

Authors

First Name

Ashraf

Last Name

El Habbak

MiddleName

Hamed

Affiliation

Professor of Ophthalmology Faculty of Medicine - Banha University

Email

ashraf_hamed23@gmail.com

City

benha

Orcid

-

First Name

Ahmed

Last Name

Saeed

MiddleName

-

Affiliation

Professor of Ophthalmology Faculty of Medicine - Banha University

Email

a_saeed775@yahoo.com

City

-

Orcid

-

First Name

Mona

Last Name

Abo ELyazeed

MiddleName

Ibrahim

Affiliation

M.B.B.Ch - Faculty of Medicine Banha University Department of Ophthalmology

Email

mona_aboelyazeed@yahoo.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Awwad

MiddleName

A

Affiliation

Assistant Professor of Ophthalmology Faculty of Medicine - Banha University

Email

mohdzahir82.ma@gmail.com

City

Benha

Orcid

0000-0001-7487-0955

Volume

42

Article Issue

3

Related Issue

54154

Issue Date

2025-03-01

Receive Date

2024-04-21

Publish Date

2025-03-01

Page Start

86

Page End

94

Print ISSN

1110-208X

Online ISSN

2357-0016

Link

https://bmfj.journals.ekb.eg/article_355402.html

Detail API

http://journals.ekb.eg?_action=service&article_code=355402

Order

9

Type

Original Article

Type Code

787

Publication Type

Journal

Publication Title

Benha Medical Journal

Publication Link

https://bmfj.journals.ekb.eg/

MainTitle

Study of the Relation between Primary Open Angle ‎Glaucoma and Serum Lipid Levels

Details

Type

Article

Created At

09 Mar 2025