With the present state of the automobile industry, vehicles need more advanced sensors for control, safety, and operation. As a result of its potential to install low-cost self-powered sensors, vibration energy harvesting has attracted significant scientific interest. In this investigation, a parametric analysis approach is presented for predicting the voltage output and harvested power for two configurations of a two-degree-of-freedom (2DOF) vibration energy harvesting system. A quarter-car suspension model with a piezoelectric element has been chosen for this investigation. The proposed models were mathematically formulated and simulated using MATLAB/Simulink. The analytical technique integrates time domain simulation and frequency response analysis methodologies, thus providing an effective way for designing, and optimizing a 2DOF piezoelectric vibration energy harvester. The energy harvesting performance is evaluated using a comprehensive parametric analysis that includes both design and operational characteristics to determine its effectiveness within the operating frequency range. The findings indicated a greater susceptibility to changes regarding harvested power bandwidth based on the suspension configurations and operating characteristics.