Aims of this study is to evaluate influence of the mixture of organic fertilizers (OF); vermicompost, bokashi EM1 and chicken manure at 33.3% from each of them was applied at R100% (7 tons fed-1) single and with seaweed liquid or vermitea as foliar spraying or soil fertigation; respectively (3, 5 and 7 times/season, respectively) to increase wheat production with minimizing of environmental pollution impacts. Two field experiments were carried out in the experimental farm of Nubaria Agricultural Research Station during the winter growing seasons of 2021/2022 and 2022/2023. Eight treatments were arranged in a randomized complete blocks design (RCBD) with 4 replicates used to study their effects on growth, yield and quality parameters. The highest significant values as an average in both two seasons were in grain yield (3.3 t/fed.), straw (4.8 t/fed.), biological yield (8.1 t/fed.), the percentage of proteins
(16.2), carbohydrates (78.3) and starch (74.4) in grain; at T8 (OF + Vermitea at 7 times/season). However, the lowest significant values as an average in both of two seasons were (1.1, 1.7 and 2.8 t/ fed., 5.6, 35.4 and 34.7%, respectively) at T1 (control). Based on observed results, a combination of OF with vermitea at 7 times/season was recommended in poor nutrients soil to maximize wheat productivity and quality.