Abstract

Background and Objectives: In the landscape of geriatric health, the intricate relationship between physical activity levels, and cardiovascular health has emerged as a focal point of research and clinical practice. This review aims to provide a comprehensive overview of the effects of physical inactivity on inflammatory markers in the geriatric population, highlighting the significance of preventive strategies and lifestyle interventions to promote cardiovascular well-being in this vulnerable population.

Research Design and Methods: Multiple databases, including PubMed, Scopus, Web of Science, Google Scholar, and Global Health were searched extensively. Studies that examined physical inactivity and cardiovascular inflammatory markers in older adults and outcomes of interest, respectively, among older adults (≥65 years) were included. PRISMA (2020) guided this review, and the findings were synthesized. This systematic review was registered in PROSPERO (CRD42024553602).

Conclusion: Addressing physical inactivity through comprehensive lifestyle interventions is a crucial public health priority. Promoting physical activity among older adults not only holds promise for lowering inflammatory markers but also represents a proactive approach to preventing cardiovascular diseases and fostering healthy aging