In this work, the kinetic parameters for MnSO₄ were studied and evaluated by the use of cyclic voltammetry (CV) in the absence and the presence of Amoxicillin by using a glassy carbon electrode (GCE). Also, the stability constant and thermodynamic parameters were evaluated for the complex formed between Mn ions with Amoxicillin. In addition, the effect of scan rate on the kinetic and thermodynamic parameters in (absence /presence) of Amoxicillin was studied. The mechanism of redox behavior was proposed for MnSO₄ that forming MnO₂ deposited at the glassy carbon electrode. The results obtained were discussed by the use of the cyclic voltammetry method.