Beta
412708

Use of tranexamic acid in simultaneous bilateral total knee arthroplasty: a comparative study

Article

Last updated: 25 Feb 2025

Subjects

-

Tags

-

Abstract

Background
Blood loss after total knee arthroplasty (TKA) is not something to neglect especially if it is bilateral. A lot of measures can be taken to reduce this blood loss such as tourniquets, autologous transfusion, and closed suction drains.
Purpose
The use of closed suction drains in TKA has downsides such as introducing a foreign body to the wound, increasing nursing care, etc. This leads to the question whether this use can be replaced by other modalities such as the use of tranexamic acid injections.
Patients and methods
Two groups of 13 patients undergoing bilateral TKA were compared. The first group had tranexamic acid injections while the other had closed suction drains. The number of transfusions and the hemoglobin drop 1 and 2 days postoperatively were assessed and compared between both groups.
Results
The hemoglobin drop both on the first and second day after the surgery were higher in the group operated with a closed suction drainage (P=0.000162 and 0.01512, respectively). The number of transfusions was also higher in the group operated with closed suction drainage (18 compared with four transfusions needed in the other group).
Conclusion
The use of drains may be replaced by tranexamic acid injections in bilateral TKA.

DOI

10.4103/eoj.EOJ_43_22

Keywords

Arthroplasty, Bilateral, Simultaneous, Total knee replacement, Tranexamic acid

Authors

First Name

Dany

Last Name

Aouad

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Mohammad

Last Name

Daher

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Mohammad

Last Name

Darwish

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Elias

Last Name

Saidy

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Lea El

Last Name

Rassi

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Georges El

Last Name

Rassi

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

Volume

57

Article Issue

4

Related Issue

53914

Issue Date

2022-10-01

Receive Date

2022-08-22

Publish Date

2023-04-14

Page Start

309

Page End

313

Print ISSN

1110-1148

Online ISSN

2090-9926

Link

https://eoj.journals.ekb.eg/article_412708.html

Detail API

http://journals.ekb.eg?_action=service&article_code=412708

Order

412,708

Publication Type

Journal

Publication Title

The Egyptian Orthopaedic Journal

Publication Link

https://eoj.journals.ekb.eg/

MainTitle

Use of tranexamic acid in simultaneous bilateral total knee arthroplasty: a comparative study

Details

Type

Article

Created At

25 Feb 2025