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412516

Treatment of chronic long-bone infections by dissolvable antibiotic beads (pure synthetic calcium sulfate impregnated with vancomycin and gentamicin)

Article

Last updated: 25 Feb 2025

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Abstract

Background
This study reviews the clinical results using synthetic calcium sulfate impregnated with vancomycin and gentamicin dissolvable beads in 70 patients who suffered from chronic long-bone infection that was not responding to several trials of treatment.
Patients and methods
All patients prepared for surgical debridement and calcium sulfate impregnated with vancomycin and gentamicin beads were inserted into the wound.
Results
The main follow-up was 12 months; the mean age of the patients was 37.94. was the organism that had been reported in 45.71% of all swabs. In the final results 61 (87.14%) patients were completely healed while only nine (12.86%) patients still had infection.
Complication
Blood loss occurred in 15 (21.42%) patients and five (7.15%) patients developed deep venous thrombosis (DVT).
Conclusion
Dissolvable beads of calcium sulfate impregnated with vancomycin and gentamicin are an effective and safe tool for the treatment of chronic long-bone infections.

DOI

10.4103/eoj.eoj_16_19

Keywords

antibiotic beads, biodegradable material, calcium sulfate, chronic osteomyelitis, Vancomycin

Authors

First Name

Ayman

Last Name

Henawy

MiddleName

T.

Affiliation

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City

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Orcid

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Volume

54

Article Issue

3

Related Issue

53898

Issue Date

2019-07-01

Publish Date

2019-07-01

Page Start

193

Page End

198

Print ISSN

1110-1148

Online ISSN

2090-9926

Link

https://eoj.journals.ekb.eg/article_412516.html

Detail API

http://journals.ekb.eg?_action=service&article_code=412516

Order

412,516

Publication Type

Journal

Publication Title

The Egyptian Orthopaedic Journal

Publication Link

https://eoj.journals.ekb.eg/

MainTitle

Treatment of chronic long-bone infections by dissolvable antibiotic beads (pure synthetic calcium sulfate impregnated with vancomycin and gentamicin)

Details

Type

Article

Created At

25 Feb 2025