Sericin is a natural, environmentally benign, proteinaceous, biodegradable biopolymer that is a by-product of the silk industry. To create a silky sheen, the degumming process needs to remove the sticky sericin from the raw silk. Many beneficial uses for sericin can be found in a variety of industries, including food, medicine, cosmetics, membranes, and biomaterials. Therefore, it is extracted using a variety of techniques. This study focuses on sericin, specifically its chemical composition, sources, properties, and extraction techniques. Additional properties and uses of sericin in textile industry are also covered one by one. It can be used to create hydrogels, films, sponges, particles and fibers with features useful in biomedical applications such as tissue engineering and wound dressing. There is also delivery. Pharmaceuticals, medical uses, biodegradability, anti-inflammatory, antibacterial, antimicrobial, antioxidant, photoprotective, flame and UV retardant.