Beta
305135

Diagnostic Value of Diffusion Tensor Imaging Indices in Assessment of Cervical Spondylotic Myelopathy

Article

Last updated: 25 Feb 2025

Subjects

-

Tags

Healthcare research

Abstract

Background: Cervical spondylotic myelopathy (CSM) develops progressively resulting from spinal cord's long-term segmental compression and it is identified by degenerative alterations to the vertebrae, intervertebral discs, facets, and related ligaments. Imaging is the most important modality to confirm the diagnosis of CSM and Magnetic resonance imaging (MRI) has become the preferred screening method for evaluation of cervical spine myelopathy. Now there is a direction to use advanced MRI techniques for more confirmation of diagnosis and better image quality, Diffusion tensor imaging (DTI) now become the most important advanced technique and diffusion properties can be assessed using the quantitative indices, apparent diffusion coefficient (ADC) and fractional anisotropy (FA), FA and ADC are the most important metrics in assessing the CSM because they are more sensitive and specific than the conventional MRI. Method: This study enrolled 30 patients with cervical spondylotic myelopathy who was diagnosed based on mJOA grading system then MRI was conducted and DTI quantitative and qualitative maps were obtained. Results: We observed a significant difference between FA & ADC metrics at stenotic and non stenotic segments and higher sensitivity and specificity of FA and ADC in diagnosing CSM over the conventional T2 hyper intense signal. Conclusion: DTI metrics are a very effective tool for quantitative evaluation of degenerative CSM.

DOI

10.21608/mjmr.2023.216038.1416

Keywords

Magnetic resonance imaging (MRI), Diffusion tensor imaging (DTI), Cervical spondylotic myelopathy (CSM), Apparent diffusion coefficient (ADC), Fractional anisotropy (FA)

Authors

First Name

Sara

Last Name

Gamal Madi Mohamed

MiddleName

-

Affiliation

Department of Diagnostic Radiology, Faculty of Medicine, Minia University, Minia, Egypt

Email

saragamalmadi1994@gmail.com

City

-

Orcid

29411062400527

First Name

Enas

Last Name

Ahmed Mohamed Abdel-gawad

MiddleName

-

Affiliation

Department of Diagnostic Radiology, Faculty of Medicine, Minia University, Minia, Egypt

Email

enasabdelgawad5@gmail.com

City

-

Orcid

-

First Name

Mohab

Last Name

Darwish

MiddleName

Mohamed Nageeb

Affiliation

Department of Surgery, Neurosurgery unit, Faculty of Medicine, Minia University, Minia, Egypt

Email

mohab.darwish@mu.edu.eg

City

minia

Orcid

0000-0002-7225-104X

First Name

Sara

Last Name

Mahmoud Ragaa Mohamed

MiddleName

-

Affiliation

Department of Diagnostic Radiology, Faculty of Medicine, Minia University, Minia, Egypt

Email

dr.sararagae1711@yahoo.com

City

-

Orcid

-

Volume

36

Article Issue

1

Related Issue

53424

Issue Date

2025-01-01

Receive Date

2023-06-13

Publish Date

2025-01-01

Page Start

84

Page End

89

Online ISSN

2682-4558

Link

https://mjmr.journals.ekb.eg/article_305135.html

Detail API

http://journals.ekb.eg?_action=service&article_code=305135

Order

35

Type

Original Article

Type Code

2,212

Publication Type

Journal

Publication Title

Minia Journal of Medical Research

Publication Link

https://mjmr.journals.ekb.eg/

MainTitle

Diagnostic Value of Diffusion Tensor Imaging Indices in Assessment of Cervical Spondylotic Myelopathy

Details

Type

Article

Created At

25 Feb 2025