Background: COVID-19 pandemic is considered as the most crucial global health calamity of the century and the greatest challenge that the humankind faced since the 2nd world war. Aim: This study aimed to identify nursing technical institute students' perception regarding coronavirus. Design: Descriptive research design was utilized to achieve the aim of this study. Sample: A convenience sample of 138 nursing students. Setting: Nursing Technical Institute, Sohag University.Tools of data collection:(1): Self-administered Questionnaire including two parts: Part 1:Demographic characteristics Part 2 :Students' knowledge regarding coronavirus. (2): Students Health Practices Tool: It consists of two parts: Part (1): Assessment of student's health practices regarding coronavirus. Part (2): Observational checklist. (3): Students attitude towards COVID-19 scale. Results : Indicated that more than half of studied students were males, more than two fifth of them their ages were  years old, less than two third were in first year. Also, it was found that less than three quarters of them were living in rural areas. there was a statistically significant positive correlation between the total knowledge of studied students and their total attitude. Also there was a statistically significant positive correlation between total knowledge of studied students and their total practices. In addition, there was a high statistically significant positive correlation between the total practice of studied students and their total attitude.  Conclusion: More than half of the studied students had satisfactory total level of knowledge about COVID 19.Also, most of the studied students had satisfactory level of total practices regarding prevention of COVID 19. In addition more than three quarters of the studied students had positive total attitude regarding COVID 19. Recommendation: Developing educational programs about COVID-19 for nursing students to improve their knowledge regarding COVID-19.