In underdeveloped nations, multidrug resistance has grown to be a serious problem. Multidrug resistance bacterial infections lead to a significant increase in patients, death and the cost of prolonged treatment. For this, there is an urgent need to design strategies to improve the antimicrobial potential of therapeutic agents. The current review aims to synthesize chitosan-coated organic Metal-Organic Frameworks (MOFs) and camel milk and use them to treat many diseases. A chitosan has activities that include the antitumor, antimicrobial, antioxidant and anti-inflammatory. These traits position them as promising therapeutic polymers. Camel milk has also shown diverse applications, affecting various aspects such as bone health, muscle function, blood standards, brain function, pancreatic activity, immune response, cancer prevention, infection resistance, metabolism, wound healing, learning, and aging. Metal-Organometallic frameworks (MOFs) are an extremely modifiable hybrid material, consisting of metal ions bound together by organic bonds that have been used as excellent drug delivery agents for cancer and many other diseases. We also highlight the role of chitosan in remove fine suspended particles and heavy metals from polluted the environment. A discovery about the power of chitosan, which was manufactured from food waste and used as a green solution to new environmental challenges.