Here, utilizing copper vanadate/zinc oxide (CuVA/ZnO) nanoparticles, we looked into the photocatalytic degradation of the dye methylene blue from an aqueous solution. For remarkable photocatalytic degradation of the dye methylene blue (MB), pure zinc oxide and copper vanadate doped zinc oxide nanopowders (5 wt.% Cu vanadate) were created. Sol-gel was used to create a single phase of zinc oxide (ZnO). Meanwhile, using a sonochemical process, the new copper vanadate nanoparticles were easily created and integrated onto the surface of ZnO. X-ray diffraction (XRD), N₂ adsorption-desorption isotherm, photo luminescence (PL), and high-resolution transmission electron microscopy (HRTEM) were used to evaluate and characterize the prepared CuVA/ZnO. Successful dispersion of the copper vanadate phase between ZnO nanocrystals was confirmed by XRD. The TEM pictures further demonstrated the hexagonal wurtzite structure of the as-produced CuVA/ZnO nanoparticles and highlighted the homogeneous integration of copper nanoparticles on the surface of ZnO. Along with an increase in ZnO's surface area, other textural metrics also improved as a result. All of the results obtained underscored the copper vanadate nanoparticles' synergistic impact on the physicochemical characteristics of ZnO. Under UV, solar, and visible light irradiations, CuVA/ZnO shown better performance against MB photodegradation.