Abstract Background: Despite being a frequent presenting com-plaint in emergency rooms, chest pain's clinical therapy varies greatly. The HEART (History, Electrocardiogram, Age, Risk factors, and initial Troponin) score is an easy-to-apply to strati-fy patients with chest pain according to their short-term risk for major adverse cardiac events (MACEs). Aim of Study: To evaluate the value and effect of the clini-cal HEART score on patient outcomes. Patients and Methods: Clinical information on 103 indi-viduals with chest pain admitted to the Emergency room March 2023 until August 2023. A prospective registry was used to re-cord information about patients with nontraumatic chest dis-comfort who were admitted from the emergency department. Results: The low-risk group, HEART score ≤3, consisted of 33/103 patients (32.1%). The high-risk population, HEART score 7-10, consisted of 26 patients (25.2%) with a moderate risk of MACE of (42.7%). Conclusion: Using the clinical HEART score during initial assessment of patients with chest pain is safe, a simple, rapid, and accurate predictor of outcome in patients with chest pain hospitalization and troponin level had a strong positive link.