Background:Climate change has been shown to pose a significant threat to mental health, by raising the risk of serious psychiatric disorders occurring or getting worse. Climate change will have a significant impact on mood disorders and their associated symptoms, which might result in neurological and psychiatric problems, as well as other types of anxiety and emotional discomfort. This study aimed to:assess climate change anxiety and its relation with coping strategies among patients with mood disorder. Subjects and methods: A descriptive correlational research design was used in this study. Purposive sample was utilized, consisting of 70 patients who have bipolar and depression disorders and accepted to share in this study. Tools of the study: Demographic data, Climate change anxiety Scale and Scale of Coping Strategies. Results: There were highly statistically significance difference between climate change anxiety, coping strategies ,depression and bipolar group. In terms of climate change anxiety, there are no appreciable variations between the two groups; nevertheless, the depression group's impairment scores were higher than those of the bipolar group. The study Concluded that: Anxiety over climate change and coping strategies for it were shown to be highly statistically significant in both the bipolar and depression groups. Recommendation: More research on climate anxiety in people with mood disorders using a bigger sample size, various instruments, and different setting is required.