A field experiment was conducted at the Experimental Farm of Sakha Agriculture Research Station, Kafr El-Sheikh, Egypt, during the 2022 and 2023 rice growing seasons, to determine the influence of foliar application of different nutrients and plant growth regulators at various growth ages on growth, yield and grain quality of Egyptian rice cultivar Giza179. The experiment was arranged in a Randomized Complete Block Design with four replications. The studied treatments consisted of a foliar spray of: control (distilled water spray), Potassium K₂O 28% (w/v) in the form of potassium phosphite at rates (2 ml/l L water), zinc 22% Zn SO₄ (w/v) in the form zinc sulfate (2 ml/ 1L water), calcium CaO 26% (w/v) in the form calcium oxide ( 2 ml/ 1 L water), cytokinin with a concentration (30 ppm), and cycocel with a concentration (400 ppm). Foliar application treatments were applied 20, 40, and 60 days after transplanting (DAT). Data showed that foliar applications of nutrients and plant growth regulators could significantly influence rice growth and yield components of Giza 179 cv. Potassium treatment seem to be more effective in improving overall plant performance. The consistent improvement across most treatments from 2022 to 2023 seasons might indicate favorable environmental conditions in the second season of the study.